Oxygen therapy

Long-term oxygen (O2) therapy is a principal therapy in stage IV (very severe) COPD. The primary goal is to increase the baseline arterial oxygen [PaO2 to at least 60 mmHg] and/or produce a haemoglobin O2 saturation (SaO2) of at least 90%.  It has been shown to prolong life in COPD patients with low O2 levels [whose PaO2 is <55 mmHg]. Continual 24-hour use is more effective than a 12-hour nocturnal regimen. O2 therapy brings haematocrit toward normal levels, moderately improves neuropsychologic factors, possibly by facilitating sleep and ameliorates pulmonary haemodynamic abnormalities. O2 therapy also increases exercise tolerance in many patients. O2 saturation should be measured during exercise and while at rest.

Reference

  1. Global Initiative for chronic obstructive lung disease: Global strategy for the diagnosis, management, and prevention of COPD. 2010. www.goldcopd.org

Chronic stable disease - drug therapy

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